Sr. /Principal Scientist, Antibody Discovery – Display Technologies  | Seattle, WA

Just is seeking a highly motivated and creative Sr. Scientist that desires a significant opportunity to help invent the technologies required to improve worldwide access to biotherapeutics. This position will be part of a cross-disciplinary team developing antibody libraries for discovery, therapeutic optimization, and high throughput characterization.  A strong foundation in molecular biology, protein display technologies, and antibody domain knowledge is required for this position. Additional experience in high-throughput methodologies, bioinformatics, and protein expression is strongly desired.  This individual must also possess strong communication and collaboration skills, a desire to learn new scientific concepts and domains, and an ability to work directly with scientific staff across multiple disciplines.

Responsibilities:

  • Work independently and in teams to develop, implement, and utilize libraries for antibody discovery and optimization
  • Design and execute antibody discovery campaigns using phage display to generate a diverse panel of antibodies
  • Perform mammalian cell culture and transient protein expression
  • Characterize antibody candidates via ELISA, AlphaLISA and other in vitro assays
  • Design and construct expression vectors using standard methodologies, such as PCR, Gibson Assembly, and ligation
  • Assist with the implementation and optimization of new high throughput technologies for more efficient and scalable workflows for antibody discovery
  • Lead and mentor a small research group
  • Maintain a detailed and organized record of experiments in an electronic notebook
  • Organize, summarize, and present data and results at department and project team meetings

Qualifications and Education Requirements:

  • B.S./M.S. with 10-20 years of experience or PhD with 5+ years of experience with training in biochemistry, cellular/molecular biology, immunology or other related discipline
  • Expertise in standard molecular biology techniques (cloning, PCR, site-directed mutagenesis, Sanger sequencing, plasmid isolation)
  • Experience with antibody discovery, protein libraries and display technologies
  • Excellent verbal and written communication skills
  • Strong focus on quality and attention to detail
  • Possess effective task/time management organizational skills
  • Ability to work in small groups as well as independently

Preferred Qualifications:

  • Experience in high throughput methodologies such as automation, microfluidics, and related bioinformatics processing
  • Experience in protein expression systems using multiple hosts
  • Experience with NGS library construction and data analysis is strongly desired
  • Experience leading a small team of scientists

About Just – Evotec Biologics

Just – Evotec Biologics, wholly-owned by Evotec SE, is a unique platform company that integrates the design, engineering, development, and manufacture of biologics. With deep experience in the fields of protein, process and manufacturing sciences, the Just team came together to solve the scientific and technical hurdles that block access to life-changing protein therapeutics; from the design of therapeutic molecules to the design of the manufacturing plants used to produce them. Just’s focus is to create access and value for a global market through scientific and technological innovation. Our state-of-the-art labs and cGMP clinical manufacturing plant are co-located in Seattle’s South Lake Union neighborhood – the center of Seattle’s medical, global health, and technology industries and a noted top emerging life science hub in the U.S. Our fast-growing team of 200 employees is expanding Just’s innovative platform and footprint – building our first North American J.POD® commercial manufacturing facility in the Seattle area. For job opportunities, learn more at www.just.bio/careers

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